Meet Isabella, a single mom to three children (5, 11 years old) and a housekeeper at a large health system. Although she is able to speak English on a basic literacy level, Isabella isn’t confident about getting the COVID vaccine due to its side effects. She relies on her 11-year old daughter to translate scientific terms. The best messaging outreach for Isabella is one that frames the motivation for getting vaccinated from decreasing personal risk to help others, thus preventing message reactance such as “Protect your family, if not yourself”.